Muscle Pain: Understanding the Mechanisms by

Language: eng
Format: azw3
Publisher: Springer Berlin Heidelberg
Published: 2010-06-20T16:00:00+00:00

Fig. 4.27 Spinal circuit underlying the gate control theory. The gate proper is represented by the inhibitory cell in the substantia gelatinosa (SG) or Rexed’s lamina II, the nociceptive transmission cell (T) and the synapses on these cells. The upper half of the figure is similar to the segmental inhibition: myelinated fibers excite the SG neuron and thus inhibit the transmission of the nociceptive activity. The unmyelinated fibers are assumed to increase the excitability of nociceptive neurons (transmission cells) in the spinal cord by inhibiting the SG cell, thus causing disinhibition (excitation) of the transmission neuron. The transmission cell is connected to other neurons which form the “action system” that elicits a variety of responses including pain if the gate is open

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